Lupus nephritis

Lupus nephritis is a kidney disorder that is a complication of systemic lupus erythematosus . It is common for people with lupus to develop a kidney disorder called "lupus nephritis" (which really just means kidney disorder caused by lupus!). Other diseases that can cause pleurisy are lung infections, such as pneumonia and tuberculosis, and other diseases such as systemic lupus erythematosus (lupus) As for the negative Lupus tests, like I said above Lupus tests can be negative too even though you may have Lupus. For starters, lupus has "subsets". The "main" lupus is SLE (systemic lupus erythematosus). Discoid Lupus (the skin related Lupus) and Systemic Lupus are two different things. -- Does anybody with lupus have neck shoulder and low back pain and stiffness and absolutely know that it's lupus related and not something else? I think they don't want to label you with lupus yet because it can be damaging to you as far as insurance goes, but they are treating with the meds that they would treat you with if you did have a lupus diagnosis.
Overview
Symptoms of lupus nephritis include : Blood in the urineFoamy appearance to urineHigh blood pressureSwelling of any area of the bodyFor general lupus symptoms , see the article on SLE . Tests to Assess Disease Activity When a person diagnosed with lupus develops new or recurring symptoms, laboratory testing of blood or urine can help determine if the symptoms are due to an increase in lupus activity.
Symptoms
The goal of treatment is to improve of kidney function . Medicines may include corticosteroids or other immunosuppressive medications.Dialysis may be needed to control symptoms of kidney failure . Insufficient kidney function may result from disorders including (but not limited to): Acute kidney failure Chronic kidney failure Lupus nephritis Transplant rejection of a kidney transplant Obstructive uropathy Glomerulonephritis Those are ALL kidney problems yielding high potassium A kidney transplant may be recommended . -LRB- People with active lupus should not have a transplant . -RRB-
Treatment
Lupus nephritis occurs when antibodies -LRB- antinuclear antibody and others -RRB- and complement build up in the kidneys , causing inflammation . I have nephritis of my kidneys caused by lupus, which means the filtering part of my kidney has been damaged enough so that it allows too much protein out into the urine. It often causes nephrotic syndrome -LRB- excessive protein excretion -RRB- and may progress rapidly to renal failure . Nitrogen waste products build up in the bloodstream.Systemic lupus erythematosus -LRB- SLE -RRB- causes various disorders of the internal structures of the kidney , including interstitial nephritis and membranous GN . Lupus nephritis affects approximately 3 out of 10,000 people . In children with SLE , about half will have some form or degree of kidney involvement.SLE is most common in women 20-40 years old . For more information , see the general article on systemic lupus erythematosus .
Causes
A physical exam shows signs of decreased kidney functioning with edema . Blood pressure may be high . Abnormal sounds may be heard when the doctor listens to the heart and lungs , indicating fluid overload.Lupus nephritis is usually discovered during investigation of the causes of reduced kidney function . Fewer than half of patients have other symptoms of SLE at the time of diagnosis of lupus nephritis.Tests that may be done include : ANA titerBUN and creatinineLupus testUrinalysisUrine immunoglobulin light chainA kidney biopsy is not used to diagnose lupus nephritis , but to determine what treatment is appropriate . Last year after lots of tests and finally a kidney biopsy I was diagnosed with Lupus Nephritis.
Tests & diagnosis
The outcome varies depending on the specific form of lupus nephritis . I have fibromyalgia and probably Lupus even though my bloodwork is not yet specific, I have several Lupus specific symptoms. Patients may have acute flare - ups with alternating symptom - free periods.Some cases of lupus nephritis may progress to chronic kidney failure.Although lupus nephritis may return in a transplanted kidney , it rarely leads to end stage kidney disease . Although kidney stones can be horribly painful and keep coming back, I don't think they actually compromise kidney function and or end up as kidney disease, which lupus nephritis definitely does.
Prognosis
There is no known prevention for lupus nephritis . These meds can promote lupus nephritis. Also, most cases of lupus nephritis occur early on after the lupus diagnosis - you do not need to have lupus for a long time for this condition to occur.
Prevention
Acute renal failureChronic renal failureEnd - stage renal diseaseNephrotic syndrome There is interstitial nephritis and renal papillary necrosis, eventually leading to acute renal failure or chronic renal failure.
Complications
Call your health care provider if blood in the urine or swelling of the body develops.If you have lupus nephritis , call your health care provider if there is decreased urine output .

Other Discussions
High Prob. Terms:
lupus disease arthritis syndrome fibromyalgia induced connective anticoagulant drug scle tissue
This writer diagnoses "lupus-like" illness, "mixed connective tissue disease," "undifferentiated connective tissue disease," and "forme fruste (meaning incipient, or hidden form) lupus".
SCLE is considered the "intermediate subset" of lupus, often milder than SLE (systemic lupus) but worse than DLE (discoid lupus).
Anyway, what I mean by the fact that FM is not DEBILITATING and Lupus is, simply that Lupus can cause organ damage, usually in it's later stages (the longer you have lived with Lupus the more damage it can do to your major organs
I was treated with methyl pred pulses and I asked to be referred to an MS specialist and he said I had atypical MS and referred me to a London Lupus Clinic were they found I had CNS Lupus
Either of the two can cause glomerulonephritis (aka nephritis, inflammation of the glomeruli of the kidneys), which can lead to proteinuria (a high concentration of protein in the urine) due to the malfunctioned filtering system and thinned capillary walls in the glomeruli which means blood protein is able to leak through

High Prob. Terms:
lupus positive patients anti discoid rash criteria ana rashes dx dna
I was referred to him because of a positive ANA blood test and he ran more specific blood tests and they came back negative for lupus, but he ran another test which came back positive for anticardiolipin antibodies which is often elevated in lupus.
SLE, systemic lupus, is the type of lupus we think of when we see the word "lupus". It is described in the "sticky post" at the front of this board, and it requires Dx in accordance with the ACR's "4 of 11" diagnostic criteria.
According to my lupus hardcover, hives are common in lupus patients: about 10% get them at least once.
Point is, some are LUPUS-SPECIFIC, which narrows down a lupus Dx fast.
There are some great "sticky posts" at the front of this board, with diagnostic criteria for lupus, a set of "alternative lupus criteria", and info on antiphospholipid syndrome, a blood clotting disorder seen in lupus or "standalone" (without lupus).